Aminul Ahmed

About

I am Senior Lecturer in Neurosurgery and a Consultant Neurosurgeon based at King’s College Hospital. My research includes investigating the use of advanced therapeutics for regeneration and repair following Traumatic Brain Injury and Spinal Cord Injury. This includes endogenous and transplanted stem cells and the use of gene therapy, including viral vector delivered treatments, in models of TBI and SCI. I am establishing a translational pathway for the use of advanced gene therapies for neurological disease, including collaborations to translate the use of vector therapy in first-in-human studies. I also use primary live human neural tissue for research and aim to foster broader collaborations within IoPPN. Overall, I am developing my translational research programme in advanced therapeutics for neurological disease and aim to translate this to neurosurgical patients at King’s College.

Work

King's College London - Guy's Campus

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Senior Lecturer in Neurosurgery

United Kingdom of Great Britain and Northern Ireland

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Education

King's College London

United Kingdom of Great Britain and Northern Ireland
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MBBS (MB/PhD)

King's College London

United Kingdom of Great Britain and Northern Ireland
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PhD

University of Cambridge

United Kingdom of Great Britain and Northern Ireland
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Publications

Does titanium cage subsidence affect clinical outcomes in ACDF surgery? A tertiary centre experience

Annals of the Royal College of Surgeons of England

journal-article

Dorsal root entry zone lesioning for brachial plexus avulsion pain: a case series

Spinal Cord Series and Cases

journal-article

Dorsal root entry zone lesioning for brachial plexus avulsion pain: a case series.

Spinal cord series and cases

journal-article

Comparison of Suspected and Confirmed Internal External Ventricular Drain-Related Infections: A Prospective Multicenter United Kingdom Observational Study.

Open forum infectious diseases

journal-article

Delivering Large-Scale Neurosurgical Studies in the UK: The Impact of Trainees

World Neurosurgery

journal-article

Does titanium cage subsidence affect clinical outcomes in ACDF surgery? A tertiary centre experience.

Annals of the Royal College of Surgeons of England

journal-article

Comparison of Suspected and Confirmed Internal External Ventricular Drain-Related Infections: A Prospective Multicenter United Kingdom Observational Study

Open Forum Infectious Diseases

journal-article

Advances in Traumatic Brain Injury Biomarkers.

Cureus

journal-article

Sonic Hedgehog Signaling Promotes Peri-Lesion Cell Proliferation and Functional Improvement after Cortical Contusion Injury.

Neurotrauma reports

journal-article

Chapter 5

Congress of Neurological Surgeons Essential Papers in Neurosurgery

book-chapter

IL-1β and HMGB1 are anti-neurogenic to endogenous neural stem cells in the sclerotic epileptic human hippocampus

ResearchSquare

other

IL-1β and HMGB1 are anti-neurogenic to endogenous neural stem cells in the sclerotic epileptic human hippocampus.

Journal of neuroinflammation

journal-article

IL-1β and HMGB1 are anti-neurogenic to endogenous neural stem cells in the sclerotic epileptic human hippocampus

Journal of Neuroinflammation

journal-article

Dorsal Root Entry Zone Lesioning for Brachial Plexus Avulsion: A Comprehensive Literature Review.

Operative neurosurgery (Hagerstown, Md.)

journal-article

Dorsal Root Entry Zone Lesioning for Brachial Plexus Avulsion: A Comprehensive Literature Review

Operative Neurosurgery

journal-article

Utility of image-guided external ventriculostomy: analysis of contemporary practice in the United Kingdom and Ireland.

Journal of neurosurgery

journal-article

Utility of image-guided external ventriculostomy: Analysis of contemporary practice in the United Kingdom and Ireland

Journal of Neurosurgery

journal-article

Age-Dependent Changes in Synaptic NMDA Receptor Composition in Adult Human Cortical Neurons

Cerebral Cortex

journal-article

Spinal cord injury: pathophysiology and strategies for regeneration

Orthopaedics and Trauma

journal-article

Spinal cord injury: pathophysiology and strategies for regeneration

Orthopaedics and Trauma

journal-article

Age-dependent changes in synaptic NMDA receptor composition in adult human cortical neurons

Cerebral Cortex

journal-article

Age dependent changes in synaptic NMDA receptor composition in adult human cortical neurons

bioRxiv

other

A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain

Molecular Brain

journal-article

Does Drain Position and Duration Influence Outcomes in Patients Undergoing Burr-Hole Evacuation of Chronic Subdural Hematoma? Lessons from a UK Multicenter Prospective Cohort Study

Neurosurgery

journal-article

Influence of Antiplatelet and Anticoagulant Drug Use on Outcomes after Chronic Subdural Hematoma Drainage

Journal of Neurotrauma

journal-article

Enduring Neuroprotective Effect of Subacute Neural Stem Cell Transplantation After Penetrating TBI

Frontiers in Neurology

journal-article

Outcomes following surgery in subgroups of comatose and very elderly patients with chronic subdural hematoma

Neurosurgical Review

journal-article

A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain

Molecular Brain

journal-article

Prospective, multicentre study of external ventricular drainage-related infections in the UK and Ireland

Journal of Neurology, Neurosurgery and Psychiatry

journal-article

The British Neurosurgical Trainee Research Collaborative: Five years on.

Acta neurochirurgica

journal-article

The British Neurosurgical Trainee Research Collaborative: Five years on

Acta Neurochirurgica

journal-article

Future of Surgery - Commissioned Report - Evidence

Royal College of Surgeons of England

standards-and-policy

Management of CSDH

Handbook of Neurosurgery, Neurology, and Spinal Medicine for Nurses and Advanced Practice Health Professionals

book-chapter

Enduring neuroprotective effect of subacute neural stem cell transplantation after penetrating TBI

Frontiers in Neurology

journal-article

Profiling biomarkers of traumatic axonal injury: From mouse to man.

Clinical neurology and neurosurgery

journal-article

Profiling biomarkers of traumatic axonal injury: From mouse to man

Clinical Neurology and Neurosurgery

journal-article

Outcomes following surgery in subgroups of comatose and very elderly patients with chronic subdural hematoma.

Neurosurgical review

journal-article

Prospective, multicentre study of external ventricular drainage-related infections in the UK and Ireland.

Journal of neurology, neurosurgery, and psychiatry

journal-article

The management and outcome for patients with chronic subdural hematoma: A prospective, multicenter, observational cohort study in the United Kingdom

Journal of Neurosurgery

journal-article

The management and outcome for patients with chronic subdural hematoma: a prospective, multicenter, observational cohort study in the United Kingdom

Journal of Neurosurgery

journal-article

Amelioration of Penetrating Ballistic-Like Brain Injury Induced Cognitive Deficits after Neuronal Differentiation of Transplanted Human Neural Stem Cells.

Journal of neurotrauma

journal-article

Amelioration of Penetrating Ballistic-Like Brain Injury Induced Cognitive Deficits after Neuronal Differentiation of Transplanted Human Neural Stem Cells

Journal of Neurotrauma

journal-article

Chronic subdural hematoma management

Handbook of Neurosurgery, Neurology, and Spinal Medicine for Nurses and Advanced Practice Health Professionals

book-chapter

Stem cells for therapy in TBI.

Journal of the Royal Army Medical Corps

journal-article

Stem cells for therapy in TBI

Journal of the Royal Army Medical Corps

journal-article

Hypothermia in Traumatic Brain Injury

Neurosurgery Clinics of North America

journal-article

Hypothermia in Traumatic Brain Injury.

Neurosurgery clinics of North America

journal-article

Endoscopic biopsy and third ventriculostomy for the management of pineal region tumors

World Neurosurgery

journal-article

Evidence to support mitochondrial neuroprotection, in severe traumatic brain injury.

Journal of bioenergetics and biomembranes

journal-article

Evidence to support mitochondrial neuroprotection, in severe traumatic brain injury

Journal of Bioenergetics and Biomembranes

journal-article

External ventricular drainage: Is it time to look at national practice?

British Journal of Neurosurgery

journal-article

Endogenous Neural Stem Cell Response to Traumatic Brain Injury

Neural Stem Cells in Health and Disease

book-chapter

Endoscopic biopsy and third ventriculostomy for the management of pineal region tumors.

World neurosurgery

journal-article

Proposal for a prospective multi-centre audit of chronic subdural haematoma management in the United Kingdom and Ireland

British Journal of Neurosurgery

journal-article

External ventricular drainage: Is it time to look at national practice?

British journal of neurosurgery

journal-article

Proposal for establishment of the UK Cranial Reconstruction Registry (UKCRR).

British journal of neurosurgery

journal-article

Proposal for establishment of the UK cranial reconstruction registry (UKCRR)

British Journal of Neurosurgery

journal-article

Proposal for a prospective multi-centre audit of chronic subdural haematoma management in the United Kingdom and Ireland.

British journal of neurosurgery

journal-article

Activation of endogenous neural stem cells after traumatic brain injury

The Lancet

journal-article

Endogenous GFAP-positive neural stem/progenitor cells in the postnatal mouse cortex are activated following traumatic brain injury.

Journal of neurotrauma

journal-article

Endogenous GFAP-positive neural stem/progenitor cells in the postnatal mouse cortex are activated following traumatic brain injury

Journal of Neurotrauma

journal-article

Stem cells in the adult human brain.

British journal of neurosurgery

journal-article

Stem cells in the adult human brain

British Journal of Neurosurgery

journal-article

Decompressive craniectomy for acute disseminated encephalomyelitis.

Neurocritical care

journal-article

Decompressive craniectomy for acute disseminated encephalomyelitis

Neurocritical Care

journal-article

Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse.

Circulation research

journal-article

Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse

Circulation Research

journal-article

Assessment of precision and reproducibility of a new myograph.

Biomedical engineering online

journal-article

Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.

PloS one

journal-article

Control of axonal growth and regeneration of sensory neurons by the p110δ PI 3-kinase

PLoS ONE

journal-article

Assessment of precision and reproducibility of a new myograph

BioMedical Engineering Online

journal-article

In vivo myograph measurement of muscle contraction at optimal length.

Biomedical engineering online

journal-article

In vivo myograph measurement of muscle contraction at optimal length

BioMedical Engineering Online

journal-article

Intracellular kinases in semaphorin signaling.

Advances in experimental medicine and biology

journal-article

Intracellular kinases in semaphorin signaling

Advances in Experimental Medicine and Biology

book

PTEN couples Sema3A signalling to growth cone collapse.

Journal of cell science

journal-article

PTEN couples Sema3A signalling to growth cone collapse

Journal of Cell Science

journal-article